在患有神经性厌食症的青少年中,血清外周炎症标志物
Hatice Ünver1, Beyzanur Gökçe Ceylan1, Ayşe Burcu Erdoğdu Yıldırım1
1Child and Adolescent Psychiatry Department, Marmara University School of Medicine, Istanbul, Turkey.
International journal of psychiatry in clinical practice
|April 22, 2024
概括
与健康个体相比,患有神经性厌食症的青少年患者的白细胞和中性粒细胞数量较低. 炎症标志物在急性神经性厌食症中不会增加,与其他心理健康状况不同.
科学领域:
- 血液学 血液学 血液学
- 精神病学是一个精神病学.
- 营养科学 营养科学
背景情况:
- 关于青少年神经性厌食症 (AN) 炎症标志物的研究有限.
- 全血细胞计和血小板参数是炎症的关键指标.
研究的目的:
- 为了比较青少年AN患者的炎症水平与健康对照.
- 为了研究身体质量指数 (BMI) 和AN中的炎症标志物之间的关系.
主要方法:
- 追溯的横截面研究.
- 对53名未经药物治疗的AN患者和53名健康对照的分析.
- 白细胞 (WBC),中性粒细胞,平均体积 (MCV),平均体积血红蛋白 (MCH),中性粒细胞/淋巴细胞比率 (NLR),血小板 (PLT) 和血小板位数 (PCT) 的比较.
主要成果:
- AN患者的WBC,中性粒细胞和NLR值显著降低.
- 两组之间没有发现与炎症相关的血小板参数的显著差异.
- 在AN患者的BMI和PLT/PCT之间观察到强烈的正相关性,这表明体重恢复后的潜在增加.
结论:
- 在神经性厌食症的急性阶段,炎症水平似乎没有增加.
- 研究结果表明,随着AN患者的营养和体重恢复,炎症标志物可能会增加.
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