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前面玻璃体在阴道炎的客观评估:一个前面的细分扫描源光学一致性断层扫描研究研究

Alessandro Invernizzi^1,2, Chiara Zaffalon³, Priscilla Manni⁴

¹Eye Clinic, Department of Biomedical and Clinical Science "Luigi Sacco", Luigi Sacco Hospital, University of Milan, Milan, Italy.

Ocular immunology and inflammation

|April 22, 2024

概括

扫描源前段光学连贯性断层扫描 (SS-ASOCT) 可以可视化前玻璃体 (AV) 炎症在脑膜炎. 在OCT检测到的AV细胞与临床炎症分级相关,提供了一个客观的评估工具.

科学领域:

眼科医生眼科眼科
医疗成像医学成像
炎症研究炎症研究

背景情况:

尿道炎是一种眼内炎症,原因多种多样.
精确的炎症分级对于有效的管理至关重要.
前玻璃体 (AV) 变化表明眼内炎症.

研究的目的:

为了评估前玻璃体 (AV) 的炎症变化,使用扫描源前段光学连贯断层扫描 (SS-ASOCT).
为了将SS-ASOCT的发现与临床紫外炎特征和眼内炎症分级相关联.

主要方法:

一项观测性,横截面研究包括140只眼睛 (96名患者):40个活跃的卵膜炎,40个不活跃的卵膜炎和60个对照.
眼内炎症是临床分级的 (前腔细胞,玻璃雾).
使用SS-ASOCT进行AV成像;手动计数OCT检测到的细胞,并间接测量玻璃体反射率 (VIT/IPE比率).

主要成果:

与不活跃的卵巢炎 (4.5±3.5) 和对照 (4±3.1) (p<0.001) 相比,活跃的卵巢炎 (12±9.8) 中前玻璃体OCT细胞的平均值显著更高.
在活跃性脑膜炎中,OCT细胞与前腔细胞呈正相关性 (p=0.04),VIT/IPE比率 (p=0.0002),脑膜炎分类 (p=0.02) 和玻璃 (p<0.0001).
平均VIT/IPE比率从对照增加到不活跃到活跃的卵膜炎,尽管从统计学上来说并不显著.

结论:

商业上可用的SS-ASOCT可以可视化和客观评估膜炎前玻璃体变化.
通过OCT检测到的前玻璃细胞可以作为客观眼内炎症评估的辅助工具.

关键词:

在前面的玻璃体.细胞细胞细胞细胞细胞这是客观的分级.光学连贯性断层扫描技术紫外线炎 (uvéitis) 是一种

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