唾液和唾液结石之间的微生物学关联在患有石病的患者中
相关实验视频
Updated: May 12, 2026

10:42
Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
Published on: December 31, 2017
17.1K
Jiwon Park1, Soo Yeon Jung2,3, Ha Yeong Kim4
1Department of Biological Sciences and Biotechnology, School of Biological Sciences, College of Natural Sciences, Chungbuk National University, Cheongju, 28644, Republic of Korea.
Scientific reports
|April 22, 2024
概括
与唾液相比,唾液石 (sialoliths) 的微生物多样性较低. 像Peptostreptococcus和Porphyromonas这样的特定细菌与结石形成相关,这表明了石病的新预防策略.
科学领域:
- 微生物学 微生物学
- 口腔生物学 口腔生物学
- 基因组学就是基因组学.
背景情况:
- 唾液结石 (sialoliths) 导致痛苦的管道阻塞,手术切除是主要的治疗方法.
- 唾液微生物群落在石病中的作用尚不清楚.
- 了解这些微生物动态对于制定预防措施至关重要.
研究的目的:
- 研究唾液结石和唾液中的微生物群落的组成和功能.
- 为了比较sialoliths患者与健康个体的口腔微生物组.
- 为了确定与sialolith形成相关的微生物因素.
主要方法:
- 唾液和唾液结石样本的16S rRNA基因测序进行比较.
- 微生物多样性,均性和丰度的分析.
- 评估石头和唾液微生物组之间的功能潜在差异.
主要成果:
- 与唾液相比,Sialoliths的微生物多样性和均性明显较低.
- 在石头和唾液中观察到Peptostreptococcus和Porphyromonas丰富度之间的积极相关性.
- 细菌化学反应和酸盐循环途径与与石头相关的基因负相关.
结论:
- 唾液结石的形成与独特的,低多样性的口腔微生物组有关.
- 特定的细菌系可能在质石病变的发病过程中发挥作用.
- 研究结果表明,可能是预防唾液结石的非手术目标.
相关概念视频
Salivary Glands and Saliva
The salivary glands, of which there are three pairs known as the parotid, submandibular, and sublingual glands, play a crucial role in maintaining oral health and initiating the digestive process. Positioned near the ears, beneath the masseter muscle, the parotid glands secrete saliva into the oral cavity through the parotid duct of Stensen. Meanwhile, the submandibular glands, located on the floor of the mouth, secrete saliva through channels named submandibular ducts. The sublingual glands,...
Urinary Tract Calculi III: Medical Management
The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
Microbiome of the Eye
The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
The Oral Microbiota
The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...

