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Updated: Jun 28, 2025

Probing RNA Structure with Dimethyl Sulfate Mutational Profiling with Sequencing In Vitro and in Cells
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Probing RNA Structure with Dimethyl Sulfate Mutational Profiling with Sequencing In Vitro and in Cells

Published on: December 9, 2022

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目标精确的RNA共识测序 (tARC-seq) 揭示了影响SARS-CoV-2分歧的复制错误机制

Catherine C Bradley1,2,3, Chen Wang1, Alasdair J E Gordon1

  • 1Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.

Nature microbiology
|April 22, 2024
PubMed
概括

一种新的测序方法,tARC-seq,精确地测量RNA病毒复制错误. 它揭示了SARS-CoV-2的突变模式和进化动态,即使是在低输入样本中.

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