在手术切除儿科视觉通路/低垂体质瘤后的并发症和视觉结果:系统性审查和元分析
Ibrahem Albalkhi1,2, Areez Shafqat1, Othman Bin-Alamer3
1College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
概括
对于症状性瘤,小儿视觉通路/下丘脑质瘤 (OPHG) 的手术切除至关重要. 虽然结果各不相同,但大多数患者会经历稳定或改善的视力,尽管像水脑这样的并发症很常见.
科学领域:
- 儿科神经瘤学 儿童神经瘤学
- 神经外科 神经外科
- 眼科医生 眼科 眼科
背景情况:
- 由于其关键位置,儿科视觉通路/下垂体质瘤 (OPHG) 存在重大管理挑战.
- 手术切除是OPHG的主要治疗方法,具有质量效应或症状,但结果数据不一致.
- 了解OPHG切除的视觉结果和并发症对于优化患者护理至关重要.
研究的目的:
- 系统地审查和分析与小儿OPHG手术切除相关的视觉结果和并发症.
- 评估儿科OPHG的总切除率和影响它们的因素.
- 为了确定OPHG切除后常见的术后并发症和瘤进展率.
主要方法:
- 在PubMed,EMBASE,Cochrane图书馆和谷歌学者中对儿科OPHG外科切除研究的系统审查.
- 包括报告视觉结果和并发症的研究,遵守PRISMA指南.
- 来自26项涉及797名儿科患者的回顾性研究数据的元分析.
主要成果:
- 在36.7%的病例中实现了总体切除,在轨道内OPHG (75.8%) 和阴/下垂体 (9.6%) 之间显著高.
- 手术后视力敏度在24.6%的患者中改善,在68.2%的患者中保持不变,在18.2%的患者中恶化.
- 常见的并发症包括水 (35.4%),前垂体功能障碍 (19.6%) 和过渡性无味糖尿病 (29%). 瘤进展发生在12.8%的患者中,平均随访时间为53.5个月.
结论:
- 手术切除是患有症状的儿科OPHG的一个重要策略,在许多情况下提供了有利的视力结果.
- 仔细的患者选择对于成功的儿科OPHG手术管理至关重要.
- 术后监测水头,瘤进展和辅助治疗的需要是必不可少的.
相关概念视频
01:25Glaucoma: Overview
560
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
560
01:22Photoreceptors and Visual Pathways
6.0K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.0K