由于Streptococcus agalactiae造成的骨科器械感染的结果:一个回顾性队列研究
Ava Diarra1, Benoit Gachet1,2, Eric Beltrand3
1Department of Infectious Diseases, Hôpital Gustave Dron, 135 rue du Président Coty, F-59200, Tourcoing, France.
BMC infectious diseases
|April 22, 2024
概括
乙组链球菌 (GBS) 假肢关节感染 (PJIs) 很少见,但与严重的并发病和高治疗失败率有关. 目前对GBS PJI的治疗方法缺乏明确的最佳策略.
科学领域:
- 传染性疾病 传染性疾病
- 整形外科手术 整形外科手术
- 微生物学 微生物学
背景情况:
- 乙组链球菌 (GBS) 是造成假肢关节感染 (PJI) 的不常见原因.
- GBS PJIs经常影响伴随疾病的患者,并与不良结果有关.
- 关于GBS PJI管理和结果的文献有限.
研究的目的:
- 调查GBS患者治疗失败的特征,治疗结果和风险因素.
- 分析GBS PJI不同管理策略的成功率.
主要方法:
- 来自两个转诊中心 (2014-2019) 的61名GBS PJI患者的回顾性分析 (2014-2019).
- 对治疗失败的描述性分析和风险因素的评估.
- 对伴随性疾病的评估,包括高血压,肥胖和糖尿病.
主要成果:
- 大多数感染 (67%) 是单微生物感染.
- 常见的并发病包括高血压 (49%),肥胖 (50%) 和糖尿病 (36%).
- 整体治疗成功率为63%,在初始治疗期间死亡率为10%. 材料的移除没有显著影响缓解.
结论:
- S. agalactiae PJI存在,并具有高的并发病率和治疗失败的显著风险.
- 没有特定的抗生素治疗方案被确定为GBS PJI治疗的优势.
- 需要进一步的研究,以建立最佳的治疗方案GBS PJI.
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