致死性粘膜炎与广泛的死引起的乳杆菌:一个案例报告
Jun Nagayama1, Takeo Sato2, Ishida Takanori3
1Advanced Medical Emergency Department and Critical Care Center, Japanese Red Cross Maebashi Hospital, 389-1, Asakura-machi, 371-0811, Maebashi, Gunma, Japan. m05071jn@jichi.ac.jp.
BMC infectious diseases
|April 22, 2024
概括
由Lactobacillus物种引起的死性纤维炎 (NF) 是罕见的,但可能发生在糖尿病和肥胖的免疫功能低下患者中. 早期诊断和手术干预对于预防广泛的组织死至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 微生物学 微生物学
- 手术病理学手术病理学
背景情况:
- 死性膜炎 (NF) 是一种严重的软组织感染,死亡率高.
- 乳酸菌种,通常具有较低的毒性,可以引起NF,特别是在免疫受损的个体中.
- 关于乳杆菌诱导的NF的临床病理学特征的数据有限.
研究的目的:
- 报告一种罕见的由乳杆菌菌种引起的NF病例.
- 突出2型糖尿病和肥胖症患者中NF的临床表现和管理.
- 强调早期诊断和干预乳杆菌诱导的NF的重要性.
主要方法:
- 一个病态肥胖的48岁妇女的病例报告,患有2型糖尿病,出现严重的大腿疼痛.
- 通过手术检查和形死证实了NF的诊断.
- 通过组织和培养物识别Lactobacillus salivarius和Lactobacillus iners.
- 管理包括新出现的手术脱bridement,抗生素,ICU护理,以及最终的皮肤移植.
主要成果:
- 患者呈现出红血,胀和严重疼痛,LRINEC得分高 (9).
- 感染是由两个乳酸菌种引起的:L. salivarius和L. iners.
- 成功的治疗涉及多次除菌,抗生素和支持性护理,导致康复.
- 患者在73天后出院,没有无助移动问题.
结论:
- 乳酸菌种可以在免疫功能低下的个体中引起罕见但严重的感染,如NF.
- 早期诊断NF,可能有助于LRINEC得分,至关重要.
- 迅速的手术干预对于预防广泛的亡和有效管理NF至关重要.
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