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Updated: Jun 28, 2025

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免疫抑制药物环素A在CD8+ T细胞中具有免疫刺激功能

Jannis Wißfeld1,2, Marvin Hering1,2,3,4,5, Nora Ten Bosch1,2

  • 1Helmholtz Institute for Translational Oncology (HI-TRON) Mainz, Mainz, Germany.

European journal of immunology
|April 22, 2024
PubMed
概括

环素A通过激活mTORC1通路来意外地刺激T细胞,这与其已知的免疫抑制作用相反. 结合氨酸和mTORC1抑制可以提高T细胞白血病的治疗结果.

关键词:
在 AKT AKT 里面.在CD8+中使用.在 CsAA CsAA核糖体蛋白质S6 核糖体蛋白质S6在T细胞,T细胞.在mTOROR中使用mTOR.

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