口腔细菌对子宫外的殖民是健康和疾病的一个新兴主题
Carla Hernández-Cabanyero1, Pascale Vonaesch1
1Department of Fundamental Microbiology, University of Lausanne, Biophore Building, UNIL-Sorge, 1015 Lausanne, Switzerland.
FEMS microbiology reviews
|April 22, 2024
概括
口腔细菌可以引起诸如IBD和癌症等全身性疾病. 本综述探讨了宫外口腔细菌殖民的分子机制及其在健康和非传染性疾病中的作用.
科学领域:
- 微生物学 微生物学
- 免疫学 免疫学 免疫学
- 遗传学 遗传学 是一个
背景情况:
- 关于口腔微生物群在全身性疾病中的作用的研究急剧增加.
- 口腔细菌越来越多地与IBD,癌症和神经系统疾病等非传染性疾病有关.
研究的目的:
- 审查和概念化关于异胎口腔细菌殖民的当前知识.
- 突出分子机制驱动殖民和维护在子宫外部口腔细菌.
- 描述口腔微生物群失生症对健康和疾病的影响.
主要方法:
- 文献综述和现有研究的综合.
- 专注于细菌殖民和宿主微生物相互作用的分子机制.
- 在不同疾病中分析共享的病理生理路径.
主要成果:
- 越来越多的证据证实了口腔细菌在各种系统性疾病中的核心作用.
- 已经发现了背后异胎殖民的新型分子机制.
- 共同的机制将口腔失生症与各种非传染性疾病联系起来.
结论:
- 了解宫外口腔细菌的殖民是预防和治疗疾病的关键.
- 需要进一步的研究来阐明从口腔失生症到全身性非传染性疾病的途径.
- 向口腔微生物群可能为系统性疾病提供新的治疗策略.
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