从微藻Haematococcus pluvialis中生产阿斯丁的新下游工艺的技术经济分析
Andreas Bauer1, Mirjana Minceva2
1Biothermodynamics, TUM School of Life Sciences, Technical University of Munich, Maximus-von-Imhof-Forum 2, 85354, Freising, Germany. msc.andreas.bauer@tum.de.
Bioresources and bioprocessing
|April 23, 2024
概括
这项研究介绍了一种新的,节能的方法,可以使用离心分区提取器 (CPE) 来从Haematococcus pluvialis微藻中提取阿斯丁. 该CPE过程显著改善了阿斯塔山丁的回收,并提供了经济上的优势比传统的提取技术.
科学领域:
- 生物技术是生物技术.
- 微藻加工 微藻加工
- 自然产品提取 提取自然产品
背景情况:
- 血球球菌 (Haematococcus pluvialis) 是一种关键的微藻,用于阿斯塔克桑的生产.
- 在H. pluvialis中,细胞内阿斯塔克桑的积累和耐药的细胞壁需要复杂的提取.
- 传统的下游加工涉及能源密集型步骤,如干燥和超临界二氧化碳提取.
研究的目的:
- 开发一种替代的,更有效的下游工艺,从H. pluvialis.提取阿斯塔山丁.
- 评估一个离心分区提取器 (CPE) 直接阿斯塔克桑回收.
- 将新型CPE工艺的技术经济可行性与传统方法进行比较.
主要方法:
- 使用离心分区提取器 (CPE) 用乙烯酸乙烯提取阿斯塔克桑丁.
- 机械破坏H. pluvialis囊细胞和发芽以释放动物.
- 四个下游加工场景的技术经济分析.
主要成果:
- 使用CPE实现了85%的阿斯塔桑提取产量.
- 从7.85g的均质化生物质中成功提取了3.5g的油脂素.
- 从发芽的动物体中提取CPE显示了10年后最高的净当前价值 (NPV).
结论:
- 基于CPE的新型下游工艺为传统的阿斯塔克桑提取提供了更节能的替代方案.
- 通过CPE直接提取乙烯酸乙烯,可以绕过能源密集的单元操作.
- 使用CPE从发芽的动物体中提取CPE是工业规模生产的最经济可行的方案.
关键词:
血球球菌 (haematococcus pluvialis) 是一种有毒的细菌.阿斯塔克桑丁是一种阿斯塔克桑丁.离心隔离器隔离器的提取方法下游加工是下游加工.液体液体色谱学 液体液体色谱学技术经济分析技术经济分析更多相关视频
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