出血类型与出血性中风后情绪和行为失控的发展之间的关系
Daniel Talmasov1, Sean Kelly1, Sarah Ecker1
1Departments of Neurology and Psychiatry, Columbia University, New York (Talmasov); Department of Neurology, New York University Langone Medical Center (Kelly, Ecker, Olivera, Lord, Gurin, Ishida, Melmed, Torres, Zhang, Frontera, Lewis).
The Journal of neuropsychiatry and clinical neurosciences
|April 23, 2024
概括
在出血性中风后,情绪和行为失控 (EBD) 是常见的,特别是在脑内出血 (ICH) 之后. 下格拉斯哥昏迷量表 (GCS) 评分预测EBD风险,表明需要对高风险患者进行早期干预.
科学领域:
- 神经学 神经学
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
背景情况:
- 情绪和行为失控 (EBD) 是中风后的一个显著的神经精神疾病并发症.
- 关于中风相关的神经精神病学后果的现有研究不成比例地关注缺血性中风.
- 流血性中风,包括脑内出血 (ICH) 和脑下出血 (SAH),也可能导致EBD,影响患者的康复和护理人员的福祉.
研究的目的:
- 为了比较脑内出血 (ICH) 和脑下下出血 (SAH) 后的EBD风险.
- 为了确定与经出血性中风后EBD发展相关的特定风险因素.
主要方法:
- 一项前性队列研究与2015年至2021年期间因非创伤性出血性中风住院的患者进行.
- 神经系统疾病生活质量 (Neuro-QOL) EBD简体清单是在住院3个月后进行的.
- 使用单变量和多变量分析来确定EBD的风险因素.
主要成果:
- 在出血性中风后3个月内,EBD的发病率为21%.
- 与SAH患者相比,患有ICH的患者患有EBD的可能性显著更高 (93%的EBD患者患有ICH).
- 较低的入院格拉斯哥昏迷量表 (GCS) 评分,较高的美国国立卫生研究院中风量表 (NIHSS) 和急性生理和慢性健康评估II (APACHE II) 评分与EBD风险增加有关.
结论:
- 脑内出血 (ICH) 和低入院格拉斯哥昏迷量表 (GCS) 评分是出血性中风后3个月EBD的显著预测指标.
- 患有ICH和低GCS得分的患者代表了发展EBD的高风险群体.
- 早期干预策略可能对被确定为患有EBD后出血性中风高风险的患者有益.
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