生命必需8和认知功能之间的关联:来自NHANES 2011-2014年的见解
Kangni Liang1, Xiaoling Zhang2
1Zhejiang Chinese Medical University, Hangzhou, China.
Frontiers in aging neuroscience
|April 23, 2024
概括
通过Life's Essential 8 (LE8) 测量,较高的心血管健康与成年人更好的认知功能有关. 这项研究发现LE8分数与认知测试的表现之间存在积极的关联.
科学领域:
- 心血管健康和认知功能
- 公共卫生和老年学
背景情况:
- 生命的基本8 (LE8) 是由美国心脏协会 (AHA) 开发的衡量标准,用于评估心血管健康.
- 在一般成年人群中,LE8与认知功能之间的关系在很大程度上仍未被探索.
- 了解这种关联对于制定促进大脑健康的公共卫生战略至关重要.
研究的目的:
- 研究生活必需品8 (LE8) 评分与多样化的成年人群中的认知功能之间的关联.
- 为了确定更高的心血管健康是否与更好的认知评估表现相关.
主要方法:
- 利用了来自全国健康和营养检查调查 (NHANES) 2,301名参与者的数据.
- 使用联盟建立阿尔茨海默病注册表 (CERAD),动物流利性测试 (AFT) 和数字符号替换测试 (DSST) 评估认知功能.
- 采用多变量线性回归和受限立方线分析来检查LE8认知关系.
主要成果:
- 较高的LE8分数与动物流利性测试 (AFT) 和数字符号替换测试 (DSST) 的表现有显著的改善有关.
- 在较高的LE8分数和CERAD分数之间观察到一个积极的关联,特别是当LE8分数超过82.5.5时.
- 多变量回归模型,调整了混因素,证明了这些显著的关系.
结论:
- 这项研究强调了最佳心血管健康之间显著的积极联系,如Life's Essential 8所示,以及成年人增强的认知功能.
- 这些发现强调了保持心血管健康的重要性,以保持整个成年期的认知能力.
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