在有氧运动期间的氧化还原信号和骨肌肉适应
Yingsong Zhou1, Xuan Zhang2, Julien S Baker3
1Faculty of Sports Science, Ningbo University, Ningbo, China.
iScience
|April 23, 2024
概括
反应性氧和物种 (RONS) 是骨肌适应运动的关键信号分子. 这篇评论探讨了RONS途径,氧化还原平衡以及它们在运动诱导的肌肉变化中的作用.
科学领域:
- 生理学 生理学 生理学
- 生物化学 生物化学
- 运动科学 运动科学
背景情况:
- 反氧调节对于依赖氧气的新陈代谢至关重要,骨肌肉是氧化酸化的中心.
- 反应性氧和物种 (RONS) 在运动诱导的肌肉适应信号中起着重要作用.
研究的目的:
- 审查通过RONS激活骨肌肉适应的分子和生化途径.
- 为了确定控制运动期间氧化还原平衡的机制.
- 讨论肌肉重塑,线粒体生物生成和血管生成中的RONS介导途径.
主要方法:
- 对氧化还原信号和运动适应研究的文献综述.
- 分析涉及RONS的分子和生化途径.
- 综合有关氧化还原平衡和外源抗氧化作用的信息.
主要成果:
- RONS作为关键信号分子,调节骨肌肉适应运动.
- 具体的途径包括线粒体生物生成,肌肉重塑,血管血管生成和神经元再生.
- 维持氧化还原平衡对于这些适应过程至关重要.
结论:
- 了解RONS介导的路径对于理解运动适应至关重要.
- 对外源性抗氧化剂的进一步研究可能为肌肉健康和性能提供治疗效益.
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