在没有认知障碍的老年人中,社交饮酒,结构性大脑衰老和认知功能之间的性别差异
Osama A Abulseoud1,2, Elisabeth C Caparelli3, Janina Krell-Roesch4,5
1Department of Psychiatry and Psychology, Mayo Clinic, Phoenix, AZ, United States.
Frontiers in psychiatry
|April 23, 2024
概括
饮酒的老年人表现出加速的大脑衰老,但有更好的认知功能. 喝酒的女性经历了与较差的语言技能相关的加速大脑衰老,这表明脆弱性.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 认知科学 认知科学
背景情况:
- 在认知健康的老年人中,研究了饮酒,大脑年龄差距和认知功能的性别差异.
- 利用了基于人口的梅奥诊所老龄化研究的数据.
研究的目的:
- 探索酒精摄入量,大脑衰老和老年人跨性别认知表现之间的关系.
- 确定酒精消费对大脑健康和认知的潜在的性别特异性影响.
主要方法:
- 通过食物频率问卷评估自我报告的酒精消费.
- 管理的认知测试涵盖了注意力,记忆,语言和视觉空间领域.
- 使用磁共振成像 (MRI) 和专用软件 (BARACUS) 估计的大脑年龄,计算大脑年龄差距.
主要成果:
- 报告酒精消费的参与者在所有认知领域的表现都超过了非饮酒者.
- 发现酒精消费与大脑年龄差距之间存在正相关性.
- 女性,但不是男性,显示大脑年龄差距和语言表现之间的负相关性.
结论:
- 酒精消费与老年人脑衰老加速有关,尽管与不饮酒者相比,酒精消费对认知有好处.
- 年长的成年女性特别容易受到伤害,脑衰老加速与语言功能下降有关.
- 研究结果强调了酒精对大脑结构和认知能力的潜在性别特异性影响.
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