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Updated: Jun 28, 2025

Overexpression and Purification of Human Cis-prenyltransferase in Escherichia coli
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一个cis-Geranylfarnesyl二酸盐合成酶的发现,结构和工程

Fang-Ru Li1, Qingling Wang1, Xingming Pan1

  • 1State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, 211198, China.

Angewandte Chemie (International ed. in English)
|April 23, 2024
PubMed
概括

研究人员从Streptomyces clavuligerus中发现了一种新的cis-geranylfarnesyl二酸盐合成酶 (ScGFPPS),能够产生C25 cis-polyisoprenoids. 这一发现扩大了已知的cis-prenyltransferases的功能,并为酶工程提供了洞察力.

关键词:
生物合成生物合成这是一种cis-geranylfarnesyl二酸盐合成酶.这是一种cis-prenyl转移酶.蛋白质工程工程 蛋白质工程

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