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Updated: Aug 10, 2026

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在纳米结构DNA中调整CpG基因的位置,以实现有效的免疫刺激

Mengmeng Tan1, Natsuki Makiguchi2, Kosuke Kusamori2

  • 1Department of Biopharmaceutics and Drug Metabolism, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan.

Biotechnology journal
|April 23, 2024
PubMed
概括

在纳米结构DNA (polypodna) 中细胞酸 - 氨酸 (CpG) 基因的位置显著影响免疫细胞刺激. 与双链区域相比,将CpG图案放置在多元的5'悬浮区域中可以增强免疫反应.

关键词:
在 CpG 中,图案是 CpG 图案.在DNA纳米结构中.免疫刺激活动的免疫刺激活动.类似于多足动物的纳米结构DNA.

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