afliberceptN-glycans

Tahereh Keshvari1,2, Stanislav Melnik1, Lin Sun1

  • 1Institute of Plant Biotechnology and Cell Biology, Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences BOKU Vienna, 1190 Vienna, Austria.

PubMed
概括

研究人员设计了植物以产生aflibercept,一种血管内皮生长因子受体 (VEGFR) 融合蛋白,通过受控的糖化. 这种基于植物的生产产生了大量的功能性aflibercept变体,为优化生物制药开发铺平了道路.

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