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Updated: Jun 28, 2025

Initiation of Metastatic Breast Carcinoma by Targeting of the Ductal Epithelium with Adenovirus-Cre: A Novel Transgenic Mouse Model of Breast Cancer
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突变RAS驱动的秘密基因导致乳腺癌骨肌肉缺陷

Ruizhong Wang1, Aditi S Khatpe1,2, Brijesh Kumar1

  • 1Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana.

Cancer research communications
|April 23, 2024
PubMed
概括

癌症亚型影响骨肌肉缺陷. 与PIK3CA不同的是,RAS路径突变显著损害肌肉功能和miR-486水平,这突显了需要考虑癌症基因组学来进行全身疗法.

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