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评估的营养状况和妊娠甲状腺功能参考范围在怀孕的第一季度在台湾怀孕
Guan-Yu Su1, Chang-Ching Yeh2,3,4, Shun-Jie Yang1
1Division of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Journal of the Chinese Medical Association : JCMA
|April 23, 2024
概括
在台湾,第一季度的营养通常是足够的,但无孕妇女和不服用多种维生素的妇女可能有缺少的风险. 确定孕期甲状腺功能范围对于怀孕期间准确诊断至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 营养科学 营养科学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
背景情况:
- 对于胎儿神经发育至关重要,特别是在头三个月.
- 在怀孕早期,甲状腺功能会发生显著的变化.
研究的目的:
- 评估台湾孕妇在怀孕第一季度的营养状况.
- 在怀孕早期建立甲状腺功能测试的参考范围.
主要方法:
- 在台北招募孕妇 (年龄≥20岁) 怀孕第一季度.
- 收集尿液样本以检测尿液中的度 (UIC) 和血液用于甲状腺功能测试.
- 使用食物频率问卷来评估饮食摄入量.
主要成果:
- 中位数UIC为160.9微克/升,表明有足够的.
- 对于TSH,自由T4,自由T3,总T4和总T3的确定的妊娠甲状腺功能参考范围.
- 确定了无卵性女性和多维生素非使用者作为低UIC (<150微克/L) 风险增加的子组.
- 如果使用非怀孕范围,则突出显示了甲状腺功能障碍的潜在错误分类.
结论:
- 在台湾,怀孕初期的状况充足,但存在有风险的子组.
- 甲状腺功能的孕期特异性参考范围对于准确诊断孕妇是必要的.
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