国际环极监测:关于Streptococcus pneumoniae的实验室间质量控制计划的更新,2009年至2020年
Alyssa R Golden1, Averil Griffith1, Brenna C Simons2
1National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.
Microbiology spectrum
|April 23, 2024
概括
国际环极监测 (ICS) 计划确保在北极地区对Streptococcus pneumoniae进行准确的测试. 这项质量控制倡议在多个实验室的血清定型和抗菌素敏感性测试中取得了很好的结果.
科学领域:
- 微生物学 微生物学
- 公共卫生监督 公共卫生监督
- 北极健康 北极健康
背景情况:
- 北极人口面临着独特的健康挑战,增加了侵入性细菌疾病的风险.
- 国际环极监测 (ICS) 计划在北极国家监测这些疾病.
- 质量控制 (QC) 程序对于监控中准确的实验室测试至关重要.
研究的目的:
- 报告ICS质量控制计划对2009年至2020年*Streptococcus pneumoniae*的结果.
- 评估参与实验室中血清型和抗菌素敏感性测试的一致性.
- 确保北极地区的参考测试服务的技术精度和准确性.
主要方法:
- 整个北极国家的六个实验室参与了ICS *S. pneumoniae* QC计划.
- 140个 *S. pneumoniae* 隔离物被分发用于血型定型和抗菌敏感性测试.
- 测试方法包括汁微稀释,Etest和光盘扩散;一致性使用CLSI和EUCAST标准进行评估.
主要成果:
- 总体血清型一致性为96.9%,个别实验室比率超过92%.
- 抗微生物敏感性测试显示所有方法和标准都具有很好的一致性 (>98%).
- 磁盘扩散测试显示出高一致性,在特定抗微生物药物方面有很小的例外.
结论:
- 该ICS质量控制计划在*S. pneumoniae*血型鉴定和抗菌感应性测试方面表现出极好的一致性.
- 持续参与质量控制计划可以保持高质量的北极群体监测.
- 这些发现支持了ICS数据在解决北极地区的健康差异方面的可靠性.
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