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Updated: Jun 28, 2025

Preparation of Rat Oligodendrocyte Progenitor Cultures and Quantification of Oligodendrogenesis Using Dual-infrared Fluorescence Scanning
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BRG1编程PRC2复合体抑制,并控制寡细胞分化和再化

Jiajia Wang1,2, Lijun Yang1, Yiwen Du2

  • 1Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

The Journal of cell biology
|April 23, 2024
PubMed
概括

染色体重塑蛋白 BRG1 在出生后大脑中对寡类细胞前体细胞 (OPC) 差异化和复髓化至关重要. 失去BRG1通过改变抑制基因的表观遗传抑制来破坏OPC分化.

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