PAR4

Sonja Kleeschulte1, Vivien Fischinger2, Lisa Öhlke3

  • 1Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital Düsseldorf, Düsseldorf, Germany.

概括

蛋白酶激活受体4 (PAR4) 驱动肥胖和白色脂肪组织 (WAT) 的炎症. 在小鼠中抑制PAR4降低了内脏脂肪和改善了葡萄糖耐受性,这表明PAR4抗剂是潜在的治疗方法.

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