"骨矿物质密度扫描中最不显著的变化是在肥胖程度较高的患者中增加的"
Claire Dorilleau1, Lukshe Kanagaratnam2,3, Isabelle Charlot1
1Rheumatology Department, University Hospital Center of Reims, 45 Rue Cognacq-Jay, Reims, Reims, 51092, France.
Aging clinical and experimental research
|April 23, 2024
概括
对于骨矿物质密度 (BMD) 扫描,最不显著变化 (LSC) 值在肥胖人群中高于一般人群. 随着身体质量指数 (BMI) 的增加,LSC增加,对于2级或3级肥胖症的建议值为0.05 g/cm2.
科学领域:
- 内分泌学 在内分泌学.
- 放射学 放射学是一门学科.
- 老年学是一门学科.
背景情况:
- 对于骨矿物质密度 (BMD) 的解释,0.03 g/cm2的标准最小显著变化 (LSC) 值可能不适用于肥胖个体.
- 肥胖会影响BMD测量的准确性和解释.
研究的目的:
- 在肥胖人口中确定 BMD 解释的适当的 LSC 值.
- 调查肥胖患者的LSC和体重指数 (BMI) 之间的关系.
主要方法:
- 一项涉及120名肥胖患者的干预研究.
- 在三个部位 (腰椎,大腿,全部) 进行了两次骨质量测量.
- 布兰德和奥尔特曼的方法被用于从对对测量计算LSC.
主要成果:
- 计算的LSC值为0.046 g/cm2 (腰椎),0.069 g/cm2 (大腿部) 和0.06 g/cm2 (整个部).
- 与较高的BMI类别相比,LSC的增加.
- 对于2级和3级肥胖症,确定了0.05g/cm2的LSC.
结论:
- 与普通人群相比,肥胖个体的LSC BMD解释门在肥胖个体中更高.
- 肥胖患者的LSC值随着BMI的增加而增加.
- 建议在2或3级肥胖患者中使用0.05g/cm2的LSC,以改善BMD扫描解读和管理.
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