非酒精性脂肪肝病与非肥胖和瘦个体的胆结石风险之间的关联
Nam Hee Kim1, Ji Hun Kang2, Hong Joo Kim1
1Division of Gastroenterology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul.
非酒精性脂肪肝 (NAFLD) 增加了胆结石的风险,即使在瘦人群中也是如此. 这表明NAFLD是胆结石形成的独立因素,无论体重如何.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 胃肠病学 胃肠病学
- 流行病学 流行病学
背景情况:
- 非酒精性脂肪肝 (NAFLD) 是一种常见的肝脏疾病.
- 在NAFLD和胆结石形成之间的联系,特别是在非肥胖个体中,并未得到充分理解.
研究的目的:
- 确定NAFLD是否是胆结石发展的独立风险因素.
- 在肥胖和非肥胖/瘦弱人群中研究这种关联.
主要方法:
- 对265,353名没有症状的成年人进行分析,这些成年人接受了腹部超声波.
- 基于肥胖和NAFLD状态的胆结石风险评估.
主要成果:
- NAFLD与胆结石风险显著增加有关 (OR,1.23).
- 这种增加的风险在非肥胖 (OR,1.29) 和瘦 (OR,1.20) 的NAFLD患者中持续存在.
- 即使在没有胰岛素抵抗的人群中,研究结果也是一致的.
结论:
- 非肥胖/瘦瘦的NAFLD是胆结石形成的独立风险因素.
- 无论肥胖程度如何,NAFLD在胆结石病变中都起作用.
- 腹部超声波检查发现肝硬化症,需要对所有患者进行彻底的胆结石评估.
更多相关视频
08:41Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
Published on: March 24, 2023
04:14Incorporation of a Survivable Liver Biopsy Procedure in Mice to Assess Non-alcoholic Steatohepatitis NASH Resolution
Published on: April 16, 2019
相关概念视频
Diseases of the Liver and Gallbladder
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Ultrasound II: Endoscopic Ultrasound and FibroScan
Endoscopic Ultrasound (EUS):
Overview of Lipid Metabolism
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Cholesterol: Significance and Regulation
Considering cholesterol and...
Obesity
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
