在上海西北地区急性缺血性中风后,认知功能障碍和血压变化风险因素之间的相关性
Meng Sun1, Zhibin Chen1, Guoyi Li1
1Shanghai Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China.
The International journal of neuroscience
|April 23, 2024
概括
脑卒中后的认知功能障碍与高水平的同等氨酸,血压变化和心脏病史有关. 一个新的模型有效地预测了针对性干预的高风险个体.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 老年学是一门学科.
背景情况:
- 认知功能障碍是急性缺血性中风后的常见并发症.
- 了解风险因素和开发预测模型对于早期干预至关重要.
研究的目的:
- 探索认知功能障碍的危险因素与急性缺血性中风患者的血压变化之间的关系.
- 为早期识别高风险个体建立预测模型,并为有针对性的预防策略提供信息.
主要方法:
- 使用斯皮尔曼相关性分析来评估血压变化和认知评估得分之间的关系.
- 部分回归系数模型和接收器运行特征 (ROC) 曲线分析被用于识别和评估独立的风险因素.
主要成果:
- 与单个因素相比,开发的临床预测模型在预测认知障碍风险方面表现出显著更高的有效性 (P <0.05).
- 鉴定到的关键预测因素包括高水平的同型半氨酸,静脉血压的高标准偏差,先前的心脏病史,以及认知功能区域的心脏病发作.
结论:
- 急性缺血性中风后的认知功能障碍与homocysteine的升高,严重的缩血压变化和特定的心脏病发作模式有关.
- 已建立的预测模型在识别患有认知功能障碍风险的患者方面具有显著价值,突出了认知功能和血压变化之间的联系.
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