烧伤患者吸入伤害的频率,并发症和死亡率:系统性审查和元分析协议
Juliana Elvira Herdy Guerra Avila1, Levy Aniceto Santana2, Denise Rabelo Suzuki3
1Culdade de Ciências de Saúde - Universidade de Brasília-UnB, Programa de Pós-Graduação em Ciências da Saúde, FaBrasilia (DF), Brazil.
PloS one
|April 23, 2024
概括
吸入伤害 (II) 显著增加烧伤患者的死亡率和并发症. 本系统性审查评估了II频率,死亡率和相关因素,以改善患者的治疗结果.
科学领域:
- 烧伤护理和创伤管理管理
- 关键护理医学 关键护理医学
- 呼吸系统药物 呼吸系统药物
背景情况:
- 烧伤是全球公共卫生问题,具有重大后果.
- 吸入伤害 (II) 是一个关键因素,使烧伤预后和治疗复杂性恶化.
- 吸入伤害往往需要侵入性机械通风 (IMV).
研究的目的:
- 评估烧伤患者吸入伤害的频率和死亡率.
- 为了评估吸入伤害与呼吸道并发症之间的关联,需要IMV和其他器官系统并发症.
- 确定与吸入伤害相关的因素和急性呼吸衰竭,IMV和死亡率的预后因素.
主要方法:
- 按照PRISMA指南进行系统的文献审查和元分析.
- 在多个数据库 (PubMed/MEDLINE,Embase,LILACS/VHL,Scopus,Web of Science,CINAHL) 中进行全面搜索,没有语言或日期限制.
- 排除有不完整数据和19岁以下患者的研究;使用连续和二分法变量进行数据综合.
主要成果:
- 吸入伤害仍然是烧伤患者发病率和死亡率的重要因素.
- 吸入伤害的诊断和损害评估是复杂的.
- 目前用于吸入伤害的治疗方法主要是支持性.
结论:
- 尽管取得了进展,但吸入伤害仍然是烧伤患者管理的重大挑战.
- 进一步的研究对于更好地了解和改善吸入伤害的结果至关重要.
- 审查协议已在PROSPERO (RD42022343944) 上注册.
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