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针对被动运动管理的端到端剂量计审计的优化得分 - 使用IROC胸部幻影仪进行的模拟研究

Alex Burton¹, Mathieu Gaudreault², Nicholas Hardcastle³

¹Australian Radiation Protection and Nuclear Safety Agency (ARPANSA), Yallambie, Victoria 3085, Australia; Department of Physical Sciences, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia; Sir Peter MacCallum Department of Oncology, the University of Melbourne, Victoria 3000, Australia; School of Science, RMIT University, Melbourne, Victoria 3000, Australia.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

|April 23, 2024

概括

对于被动运动管理的剂量计审计需要动态测量. 在IROC幻影中的感兴趣区域马分析对规划和交付错误的敏感性比整片分析更高.

科学领域:

医学物理医学物理
辐射瘤学辐射瘤学
放射治疗物理物理

背景情况:

剂量计审计对于放射治疗中的被动运动管理至关重要.
将动态测量与静态计划剂量进行比较至关重要.
目前的审计评分方法需要对准确性进行评估.

研究的目的:

描述计划/分娩错误与移动幻影中测量剂量之间的关系.
评估不同审计评分方法对被动运动管理的有效性.
评估各种指标对引入的错误的敏感性.

主要方法:

使用成像和辐射瘤核心 (IROC) 胸部幻影与片和热发光剂量计 (TLD).
使用4DCT数据和通过异心位移模拟运动创建了治疗计划 (DCAT,VMATLo,VMATHi).
引入的错误 (设置位置,目标划分) 和使用马分析在感兴趣区域 (ROI) 和整个片平面内分析的膜剂量.

主要成果:

即使没有引入错误,也观察到运动诱导的剂量差异.
在以目标为中心的ROI中,马传递率与错误诱导的剂量差异有很好的相关性,而不是整个片的传递率.
基于异位剂的设置位置测量对错误非常敏感,而TLD点剂量显示出不稳定的反应.

结论:

感兴趣区域 (ROI) 马分析与整片分析相比,对模拟错误具有更高的灵敏度.
通过结合设置位置或最大马等指标,可以改进马分析结果.
对于被动运动管理的审计评分可能会从基于ROI的马分析和补充错误指标中受益.

关键词:

剂量测量审计的审计马分析的研究结果.运动管理运动管理

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