与代谢功能障碍相关的脂肪性肝病患者的心电图异常:系统性审查和元分析
Christian Akem Dimala1, Nso Nso2, Jeremiah Wasserlauf3
1Division of Cardiovascular Medicine, University of Texas Medical Branch, 301 University Blvd., 5.106 John Sealy Annex, Galveston, TX 77555-0553, United States.
Current problems in cardiology
|April 23, 2024
概括
代谢功能障碍相关的脂肪性肝病 (MASLD) 与许多心电图 (ECG) 异常有关. 这些心电图变化可能是早期心脏病的信号,并有助于对MASLD患者的风险分层.
科学领域:
- 心脏病学 心脏病学
- 肝病学 肝病学是一种肝病学.
- 代谢疾病 代谢疾病
背景情况:
- 代谢功能障碍相关的脂肪性肝病 (MASLD),以前称为NAFLD,因其系统性影响而越来越受认可.
- 了解MASLD对心脏的影响对于全面的患者管理至关重要.
研究的目的:
- 系统地审查和综合目前有关MASLD患者心电图 (ECG) 异常的证据.
- 为了确定与MASLD相关的特定的ECG模式.
- 探索心电图发现在MASLD患者心脏风险分层中的潜力.
主要方法:
- 从1946年到2023年发表的研究的系统审查.
- 包括检查MASLD和ECG异常之间的关联的研究.
- 从符合条件的研究中提取,分析,综合和总结数据.
主要成果:
- 分析了27项涉及超过860万参与者的研究 (MASLD有100万参与者).
- 在MASLD和心房动,更短的QRS持续时间,QTc延长,LVH,低电压,ST变化,T波逆转,轴偏差,导电缺陷,捆绑分支阻塞,心脏阻塞,碎片化QRS和p波分散之间发现了统计学意义上的关联.
- 多个ECG异常被确定为MASLD中心脏参与的潜在早期标志物.
结论:
- MASLD与广泛的心电图异常有关,表明潜在的早期心脏参与.
- 这些心电图发现可以作为MASLD患者心脏风险分层的有价值标记.
- 承认这些关联强调了MASLD的多系统性质.
更多相关视频
07:12Author Spotlight: Analysis of Fluorescent-Stained Lipid Droplets with 3D Reconstruction for Hepatic Steatosis Assessment
Published on: June 2, 2023
6.5K
08:41Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
Published on: March 24, 2023
1.1K
相关概念视频
01:29Electrocardiogram
2.3K
An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
2.3K
01:28Electrocardiogram Fundamentals
572
Introduction
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin...
572
01:28Disturbances in Heart Rhythm
945
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
945
01:25Ultrasound II: Endoscopic Ultrasound and FibroScan
102
Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):
Endoscopic Ultrasound (EUS):
102
01:24Overview of Lipid Metabolism
1.5K
Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
1.5K
01:28Mechanism of Cardiac Arrhythmias
917
Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
917