维生素D缺乏症与良性发性位置性 (BPPV) 发生率和复发之间的关联:系统性审查和元分析
Heather Wood1, Karolina Kluk2, Ghada BinKhamis3,4
1College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.
BMJ open
|April 23, 2024
概括
这项研究发现,较低的维生素D水平与新出现的良性发性位置性 (BPPV) 病例有关. 然而,维生素D与复发性BPPV之间的联系仍然不清楚.
科学领域:
- 神经学 神经学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 良性性发性位置性 (BPPV) 是一种常见的前体障碍.
- 维生素D缺乏很普遍,可能会影响各种健康结果.
- 了解与BPPV发病率和复发相关的因素对于预防和管理至关重要.
研究的目的:
- 调查血清维生素D水平与BPPV发病率风险之间的关系.
- 检查血清维生素D水平与BPPV复发之间的关联.
- 通过系统审查和元分析来综合现有证据.
主要方法:
- 2000年至2023年间发表的研究的系统审查和元分析.
- 在PubMed,Scopus和Web of Science数据库中进行了搜索.
- 包括北半球BPPV个体的研究和测量维生素D水平,但不包括患有并发症或补充剂的人.
主要成果:
- 包括35篇文章,其中包含来自9843个人的数据.
- 与对照组相比,在BPPV发病率较低的人群中发现血清维生素D水平较低.
- 维生素D水平与BPPV复发之间的关系不确定.
结论:
- 血清维生素D水平与BPPV发病率有负相关.
- 关于维生素D和BPPV复发之间的关联的证据是不确定的.
- 需要进一步的研究来探索潜在的混因素,如季节性.
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