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Updated: Jul 19, 2026

Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium
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整合瘤和健康的上皮在微生理学多部件的方法来研究细胞癌的病理生理学

Maryna Somova1, Stefan Simm2,3, Adventina Padmyastuti1

  • 1Department of Urology, University Medicine Greifswald, DZ7 J05.15, Fleischmannstraße 8, 17475, Greifswald, Germany.

Scientific reports
|April 23, 2024
PubMed
概括

这项研究使用微生理系统 (MPS) 开发了一种先进的体外脏细胞癌 (RCC) 模型. 该模型模仿瘤与宿主之间的相互作用,揭示了癌研究中的代谢转变和免疫因子变化.

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Renal Tubule and Collecting Duct01:24

Renal Tubule and Collecting Duct

The renal tubule is divided into three parts: the proximal convoluted tubule (PCT), the Loop of Henle (LOH), and the distal convoluted tubule (DCT).
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...