2012年至2023年哈萨克斯坦肝移植服务的评估
Yuliya Semenova1, Altynay Beyembetova2, Saule Shaisultanova3
1School of Medicine, Nazarbayev University, 010000, Astana, Kazakhstan.
Scientific reports
|April 23, 2024
概括
哈萨克斯坦 哈萨克斯坦 哈萨克斯坦
科学领域:
- 肝病学 肝病学是一种肝病学.
- 移植手术 移植手术
- 公共卫生政策 公共卫生政策
背景情况:
- 关于哈萨克斯坦国家肝脏移植 (LTx) 计划的表现的数据有限.
- 病毒性肝炎和肝硬化患病率上升需要对LTx服务进行评估.
- 了解LTx趋势对于解决哈萨克斯坦患者需求至关重要.
研究的目的:
- 评估2012年至2023年哈萨克斯坦国家肝移植计划的表现.
- 分析LTx手术,移植中心和等待列表动态的趋势.
- 预测未来的发展,并确定关键的干预需求.
主要方法:
- 对LTx数据 (2012-2023) 的回顾性分析.
- 对于等待LTx.患者的生存分析 (生命表,Kaplan-Meier)
- 对到2030年的预测进行时间序列分析.
主要成果:
- 每百万人口的LTx率各不相同 (0.35-3.77),有利于活体捐赠者.
- 在等待名单上生存率:30天 (87.0%),1年 (68.0%).
- 在474名患者中,有364名患者在等待LTx的显著滞后.
结论:
- 哈萨克斯坦的LTx计划面临着日益增长的积压挑战.
- 肝病发病率上升和稳定的移植率可能会使情况恶化.
- 需要紧急的战略干预来改善LTx的访问和结果.
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