在手术前的乳酸水平和手术后的早期并发症之间存在关联,因为孤立的四肢骨折
Yusho Nishida1, Ryo Yamamoto2, Soichiro Ono2
1Department of Emergency and Critical Care Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo, 160-8582, Japan. yushonishida@keio.jp.
在孤立的四肢骨折中,术前乳酸盐水平升高 (≥2 mmol/L) 预测了早期的术后并发症的增加,特别是在早期手术中. 这一发现有助于为骨折患者做出手术时间决定.
科学领域:
- 整形外科手术 整形外科手术
- 创伤护理 创伤护理
- 生物标志物研究 生物标志物研究
背景情况:
- 乳酸盐水平对孤立四肢骨折手术结果的预测价值尚未得到充分确立.
- 骨折骨科手术后的早期术后并发症需要更好的预测工具.
研究的目的:
- 为了研究手术前乳酸水平与患有孤立四肢骨折的患者早期术后并发症之间的关联.
- 确定手术前的乳酸盐水平是否可以指导确定骨科手术的时间.
主要方法:
- 追溯观察性研究包括187名患有孤立四肢骨折的患者.
- 乳酸水平在手术前24小时内进行评估;乳酸≥2 mmol/L和<2 mmol/L组之间的并发症比较.
- 亚组分析考虑了手术和骨折类型的时间.
主要成果:
- 在手术前乳糖≥2 mmol/L的患者中,早期术后并发症的发生率显著更高.
- 在调整年龄和受伤严重程度后,这种关联仍然存在.
- 在手术前的高乳酸水平与在到达6小时内接受手术的患者的并发症增加有关.
结论:
- 术前乳酸水平≥2 mmol/L与孤立四肢骨折的早期术后并发症增加有关.
- 这种关联在入院6小时内获得最终固定的患者中尤为明显.
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