抑郁症的动态性与下泌尿道症状之间的纵向关联表明良性前列腺增生 (LUTS/BPH)
Zonglan Xie1, Xuebin Liu1, Zhigang Hu2
1Department of Urology, The First Dongguan Affiliated Hospital, Guangdong Medical University, Jiaoping Road No. 42, 523710, Dongguan, People's Republic of China.
BMC public health
|April 23, 2024
概括
慢性主要抑郁症显著增加了患上下泌尿道症状的风险,这些症状暗示着良性前列腺增生 (LUTS/BPH). 管理抑郁症对于预防男性的LUTS/BPH至关重要.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 抑郁症与较低尿路症状的风险增加有关,这些症状暗示良性前列腺增生 (LUTS/BPH).
- 抑郁症的动态性对LUTS/BPH发病率的影响尚不清楚.
研究的目的:
- 研究抑郁症的动态性质与LUTS/BPH的发病率之间的关联.
- 评估不同的抑郁轨迹是否会影响LUTS/BPH的发展.
主要方法:
- 一项为期四年的队列研究,使用来自中国健康与退休纵向研究 (CHARLS) 的数据,对3433名中国男性进行了研究.
- 抑郁动态分为急性缓解,急性复发或慢性严重抑郁.
- 权重的通用添加模型分析了LUTS/BPH和抑郁模式之间的关系.
主要成果:
- 新发病的LUTS/BPH在四年内在11.5%的参与者中被诊断出.
- 与没有抑郁症相比,慢性主要抑郁症显著增加了LUTS/BPH发生率 (RR=1.63,P<0.01).
- 这种联系在60岁以下的中国男性中尤为明显.
结论:
- 抑郁症的动态性质对LUTS/BPH发病率产生不同影响.
- 监测和治疗抑郁症是预防LUTS/BPH的重要策略.
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