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Updated: Jun 28, 2025

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对患有PALB2致病变体的个体乳腺癌风险的元分析

Thanthirige L M Ruberu1, Danielle Braun2,3, Giovanni Parmigiani2,3

  • 1Department of Mathematical Sciences, University of Texas at Dallas, Richardson, USA.

Genetic epidemiology
|April 23, 2024
PubMed
概括

在PALB2基因的致病变体显著增加乳腺癌 (BC) 的风险. 这一元分析估计了50岁 (12.80%) 和80岁 (48.47%) 的PALB2突变载体的BC风险,有助于临床管理.

关键词:
贝叶斯模型是贝叶斯模型.赔率比率 赔率比率 的比率.病原性变体的病原性变体穿透 穿透 穿透 穿透 穿透相对风险是相对风险.

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Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
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