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Updated: Jun 28, 2025

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
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Published on: August 20, 2019

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人类中TBC1D3基因家族的独立扩展,选择和超变性

Xavi Guitart1, David Porubsky1, DongAhn Yoo1

  • 1Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, USA.

bioRxiv : the preprint server for biology
|April 24, 2024
PubMed
概括

灵长类动物特异的TBC1D3基因家族在人类中扩大,影响了额叶皮层的发育. 尽管拷贝数量和结构具有很高的变异性,但人类TBC1D3的表达受到限制,这可能解释了人口差异.

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