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免疫细胞和结性脊髓炎之间的因果关系:单变,双向和多变的门德尔随机化

Chaofan Qin1, Qingshuai Yu1, Zhongliang Deng1

  • 1Department of Orthopedics, Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.

Frontiers in immunology
|April 24, 2024
PubMed
概括

门德尔的随机化确定了与结性脊髓炎 (AS) 风险相关的特定免疫细胞. 在CD33dim HLA DR+ CD11b+细胞上的HLA DR降低了AS风险,而在效应记忆CD8+ T细胞上的CD8增加了AS风险.

关键词:
结性脊柱炎是一种疾病.双向的门德尔式随机化免疫细胞 免疫细胞多变量 门德尔式随机化单变量 门德尔随机化

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