分隔剂量与全剂量肠道制备使用聚乙烯糖醇进行结肠镜检查:一个多中心的前性黎巴嫩随机试验在2021年至2023年之间
Blaybel Sara1, Hammoud Ghinwa1, Mourda Layla1
1Department of Internal Medicine, Faculty of Medical Sciences Lebanese University Hadat Lebanon.
Health science reports
|April 24, 2024
概括
与前一天的结肠镜检查方案相比,分剂量聚乙烯糖醇 (PEG) 肠道制剂显示出类似的疗效和患者满意度. 需要进一步的研究,以优化为个别患者准备.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 临床试验研究 临床试验研究
背景情况:
- 肠道准备是结肠镜检查过程中至关重要的,但往往令人担忧的组成部分.
- 优化肠道清洁对于有效的结肠镜检查和患者舒适性至关重要.
- 评估不同的聚乙烯甘醇 (PEG) 给药方案是改善患者体验的关键.
研究的目的:
- 为了比较分剂PEG与前一天的结肠清洁疗程的疗效.
- 评估患者对两种肠道制备方法的满意度.
- 为了确定两种PEG疗法之间的不良事件的潜在差异.
主要方法:
- 一项随机研究涉及200名接受结肠镜检查的住院患者.
- 组A接受了两天分剂量PEG制剂;组B接受了单剂量 (前一天) PEG制剂.
- 使用波士顿肠道准备量表 (BBPS) 评估结肠清洁,并记录患者的满意度.
主要成果:
- 在分割剂量和前一天PEG组之间的波士顿肠准备量表得分中没有观察到统计学上显著的差异 (p=0.162).
- 两组患者的患者满意度得分也相似 (p=0.896).
- 在睡眠障碍方面发现了显著的差异,分剂组中较少的患者报告了这种不良事件 (20.4%与33.3%,p=0.040).
结论:
- 分剂和前一天的PEG肠道制备方案都显示出类似的疗效和患者满意度对结肠镜检查.
- 分剂疗法可能与睡眠障碍的减少有关.
- 需要进一步的研究来确定最佳的肠道准备策略,考虑到个体患者的因素.
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