在引入DTaP-IPV/Hib组合疫苗后,婴儿疫苗接种实践的变化
Hee-Jin Kim1, Suvin Park1, Na-Young Jeong1
1Department of Health Convergence, Ewha Womans University, Seoul, Republic of Korea.
Vaccine: X
|April 24, 2024
概括
在韩国引入DTaP-IPV/Hib组合疫苗后,婴儿疫苗接种率显著增加. 这一转变减少了婴儿免疫计划所需的医疗访问的平均数量.
科学领域:
- 儿科 儿科 儿科
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
背景情况:
- 2017年6月,疹 - 结核病 - 细胞性百日咳,脊髓灰质炎和乙型流感 (DTaP-IPV/Hib) 组合疫苗被纳入韩国国家免疫计划 (NIP).
- 组合疫苗简化了免疫接种计划,有可能提高疫苗接种率.
研究的目的:
- 评估DTaP-IPV/Hib组合疫苗的引入对韩国NIP内的婴儿疫苗接种实践的影响.
- 分析初级DTaP,IPV和Hib疫苗系列完成率的变化以及与疫苗接种相关的医疗访问的频率.
主要方法:
- 全国范围的疫苗注册表被用于分析2013年至2019年间出生婴儿的数据.
- 该研究估计了在12个月内完成DTaP,IPV和Hib (D-I-H) 初级系列的婴儿比例.
- 疫苗接种模式和医疗访问的频率在引入前和引入后的出生队列之间进行了比较 (2013-2016 vs. 2017-2019).
主要成果:
- 在2,703,822名婴儿中,96.7%的婴儿在12个月内完成了初级D-I-H系列.
- 在2017年之前,大多数婴儿接受了仅DTaP-IPV疫苗 (75.4%);在引入后,大多数接受了仅DTaP-IPV/Hib (81.0%).
- 在不同DTaP组件组之间观察到疫苗接种医疗访问的平均频率的统计学上显著差异 (p < 0.001).
结论:
- DTaP-IPV/Hib组合疫苗促进了婴儿初级D-I-H系列的更高完成率.
- 引入组合疫苗导致婴儿接种疫苗的医疗访问平均数量显著下降.
- 研究结果为其他国家提供了宝贵的见解,这些国家正在考虑在国家免疫计划中采用组合疫苗.
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