体重指数影响与年龄相关的白内障:更新的元分析和系统性审查
Huilin Chen1,2, Xiaolei Sun3,3, Li Pei4
1Department of Medical College, Qingdao University, Qingdao, China.
Arquivos brasileiros de oftalmologia
|April 24, 2024
概括
这项元分析发现,超重与与年龄相关的白内障风险降低有关. 然而,肥胖可能会增加某些白内障类型的风险.
科学领域:
- 眼科医生 眼科 眼科
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 在全球范围内,白内障导致明显的视力障碍和失明.
- 与年龄相关的白内障的危险因素包括年龄,吸烟,酒精和紫外线辐射暴露.
研究的目的:
- 进行一项元分析,评估身体质量指数 (BMI) 和与年龄相关的白内障之间的关联.
主要方法:
- 2011年1月至2020年7月期间发表的研究的系统审查.
- 在PubMed,Medline和Web of Science数据库中搜索相关研究.
- 采用随机效应和固定效应模型进行元分析,将结果报告为几率比率 (OR).
主要成果:
- 包括9项研究. 体重不足与核白内障没有相关性 (OR=1.31,p=0.156).
- 超重与与年龄相关的白内障 (OR=0.91,p<0.0001) 的风险降低以及皮质,核和后部亚囊白内障的风险显著相关.
- 肥胖与皮质性 (OR=1.00),核性 (OR=1.07) 和后部亚囊性白内障 (OR=1.14) 的风险增加有显著的相关性.
结论:
- 体重指数与与年龄相关的白内障有显著的相关性.
- 超重似乎降低了白内障风险,而肥胖可能会增加它.
- 需要进一步的研究来阐明BMI和白内障发展之间的复杂关系.
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