影响先天性梅毒诊断测试阳性性的因素
Rodrigo Soares Ribeiro1, Natália Sperli Geraldes Marin Dos Santos Sasaki1, Alessandra Marinela de Abreu Queiroz1
1Faculty of Medicine of São José do Rio Preto - São José do Rio Preto (SP), Brazil.
概括
在农村的婴儿和那些母亲在出生后被诊断出患有梅毒的婴儿中,先天性梅毒测试的阳性率更高. 产前查对于预防并发症至关重要.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染性疾病 传染性疾病
背景情况:
- 先天性梅毒对新生儿构成重大风险.
- 准确的诊断测试对于及时干预至关重要.
研究的目的:
- 在先天性梅毒病例中确定与特雷波内马和非特雷波内马检测结果阳性相关的因素.
- 了解母亲和地理因素对诊断测试阳性的影响.
主要方法:
- 从巴西的SINAN数据库分析了639个先天性梅毒通知 (2007-2018) 的横截面和相关性研究.
- 描述性和推断性统计分析,包括后勤回归 (p≤0.05).
主要成果:
- 来自农村地区的婴儿中,特雷波内马尔测试阳性是农村地区婴儿的4.5倍.
- 产后的母性梅毒诊断增加了三角膜体检阳性率的19.6倍.
- 晚期诊断出孕产妇梅毒 (2007-2015年和产后) 与较高的三角膜试验阳性有显著的相关性.
结论:
- 在产前护理期间早期发现梅毒对于预防不良结果至关重要.
- 农村居住和母亲诊断迟到等因素会影响先天性梅毒测试的阳性.
- 加强产前查计划可以减轻先天性梅毒的并发症.
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