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全身振动刺激对老年人的血溶性TNF受体的影响:一个随机对照试验

H C Almeida¹, V K S Lage², R Taiar³

¹Programa de Pós-Graduação Multicêntrico em Ciências Fisiológicas, Sociedade Brasileira de Fisiologia, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Diamantina, MG, Brasil.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas

|April 24, 2024

概括

全身振动炼 (WBV) 严重影响炎症标志物,特别是增加可溶性瘤缩因子受体2 (sTNFR2) 在非sarcopenic和sarcopenic老年人中. 麻症患者对WBV的反应更为明显.

科学领域:

老年学是指老年学的学科.
运动生理学运动生理学
免疫学免疫学免疫学

背景情况:

标志着与年龄相关的肌肉质量和力量损失的萨尔科佩尼亚严重影响老年人的生活质量.
身体炼干预措施对于管理肉症至关重要,研究正在探索各种模式.
炎症标志物在肉病原和对运动的反应中起作用.

研究的目的:

为了比较全身振动运动 (WBV) 对非肉骨 (NSG) 和肉骨老年人 (SG) 炎症参数的急性影响.
研究WBV在NSG和SG之间对血溶性瘤亡因子受体 (sTNFR) 的差异影响.

主要方法:

一项随机控制的交叉研究,涉及44名老年参与者 (22 NSG, 22 SG).
参与者接受了两种方案:使用WBV进行式炼和不使用WBV进行式炼,两者之间有洗期.
在干预前和后使用ELISA测量了血sTNFR水平. 身体组成和身体功能也被评估.

主要成果:

一次急性WBV会话在NSG和SG组中显著增加了sTNFR2水平 (P<0.01).
与非sarcopenic个体相比,sarcopenic个体在WBV后的sTNFR2水平增加得更大 (d=-0.95对d=-0.69).
这些发现表明,在患有肉症的个体中,对WBV的炎症反应更为明显.

结论:

急性全身振动运动有效地影响sTNFR2水平,表明炎症反应.
随着WBV的出现,sarcopenic老年人表现出sTNFR2水平的高反应,这表明敏感性更高.
WBV成为一种潜在的有效炼策略,用于管理与年龄相关的疾病,如肉症和相关的炎症过程.

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