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补充Enterococcus faecium可以预防山羊中大肠杆菌引起的肠炎
J Dong1,2,3, Y Jiang4,5, Z Li1,2,3
1College of Veterinary Medicine, Yangzhou University, Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, 225009 Yangzhou, China P.R.
Beneficial microbes
|April 24, 2024
概括
补充Enterococcus faecium可以通过改善临床症状和肠道健康来保护山羊免受大肠杆菌诱导的肠炎. 这种益生菌增强肠道完整性,减少炎症,有利于牲畜健康.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 微生物学 微生物学
- 动物营养 动物营养
背景情况:
- 菌 (Enterococcus faecium) 是一种有益的肠道微生物,具有已知的免疫调节特性.
- 大肠杆菌是一种重要的病原体,在动物,包括山羊中引起炎症性肠病.
- 肠炎对山羊的健康和生产力构成重大威胁.
研究的目的:
- 为了研究Enterococcus faecium对山羊中的大肠杆菌诱导肠炎的保护作用.
- 评估E. faecium对生理参数,肠道病理和微生物群平衡的影响.
主要方法:
- 40只山羊被分为四组:对照组,E. faecium,大肠杆菌和E. faecium + E. coli. 大肠杆菌.
- 评估了生理指标,腹得分,病理检查和炎症性细胞因子mRNA表达.
- 分析了叶内和阴中的细菌数量.
主要成果:
- 大肠杆菌感染导致体温,呼吸率,心率,白细胞计数和腹得分的增加.
- E. faecium 预处理缓解了这些临床症状,并减少了他的病理损伤.
- 便补充剂降低了大肠杆菌负载,增加了乳杆菌的患病率,并抑制了炎症标志物 (TLR4,IL-1β,IL-6,IL-8,TNF-α).
结论:
- 补充Enterococcus faecium对患有大肠杆菌引起的肠损伤的山羊有益.
- E. faecium可以改善临床症状,保持肠道粘膜完整性,平衡肠道微生物群.
- 益生菌E. faecium有效地减少了山羊肠中的炎症反应.
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