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相关概念视频

Role of Hippocampus in Memory01:19

Role of Hippocampus in Memory

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The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
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Olfaction01:25

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The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
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相关实验视频

Updated: Jun 28, 2025

High-resolution In Vivo Manual Segmentation Protocol for Human Hippocampal Subfields Using 3T Magnetic Resonance Imaging
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在缓解的精神分裂症中,海马体的子领域.

Ying-Jay Liou1,2, Mu-N Liu1,2, Kai-Chun Yang1,2

  • 1Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.

Journal of the Chinese Medical Association : JCMA
|April 24, 2024
PubMed
概括

精神分裂症患者的海马体积减少,特别是在尾部. 这些大脑变化与症状缓解有关,并可能作为疾病的生物标志物.

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科学领域:

  • 神经科学是一个神经科学.
  • 精神病学是一个精神病学.
  • 放射学 放射学是一门学科.

背景情况:

  • 关于精神分裂症中海马亚区域体积变化存在不一致的证据.
  • 很少有研究探讨了海马体积与精神分裂症症状缓解之间的联系.

研究的目的:

  • 研究与健康对照组相比,精神分裂症患者的区域海马体积差异.
  • 检查海马体积与精神分裂症症状缓解之间的关系.

主要方法:

  • 与31名精神分裂症患者和31名健康对照进行的横截面研究.
  • 使用手动和自动技术测量海马子区域和子场体积.
  • 用于统计分析的协差的多变量和单变量分析.

主要成果:

  • 精神分裂症患者呈现较小的双边海马头和尾在纵向上.
  • 在患者的多个横向海马子场 (例如,CA1,CA3,CA4) 中观察到体积减少.
  • 与缓解症患者和对照患者相比,非缓解性精神分裂症患者的双边海马尾部子场较小.

结论:

  • 精神分裂症的病理生理学和症状缓解与海马细分体积变化有关.
  • 这些海马体积变化可能具有临床意义,作为精神分裂症识别和治疗的生物标志物.