短期补充Aronia melanocarpa提取物可以改善认知表现:一项随机,双盲,安慰剂控制的交叉研究,针对健康的年轻成年人进行
Sanne Ahles1,2, Peter J Joris1, Jogchum Plat3
1Department of Nutrition and Movement Sciences, Institute of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, 6200 MD, Maastricht, The Netherlands.
European journal of nutrition
|April 24, 2024
概括
短期服用Aronia melanocarpa提取物 (AME) 补充剂改善了年轻成年人的注意力和精神运动速度. 这种认知增强与血清中脑衍生神经营养因子 (BDNF) 水平的增加有关.
科学领域:
- 营养神经科学 营养神经科学
- 认知增强 认知增强
- 食补充剂 食补充剂
背景情况:
- 富含圣素的食物对认知效益的研究主要是在老年人身上进行的.
- 关于年轻人群体的短期认知影响的研究有限.
- 阿罗尼亚梅拉诺卡帕提取物 (AME) 含有丰富的抗素.
研究的目的:
- 研究AME补充剂对健康年轻人认知表现的短期影响.
- 探索潜在的潜在机制,包括BDNF水平和血管功能.
- 解决关于年轻成年人和短期补充剂的研究差距.
主要方法:
- 随机,双盲,安慰剂控制的交叉研究,对35名健康的年轻成年人进行了随机,双盲,安慰剂控制的交叉研究.
- 一周补充AME (180毫克安托西亚宁/天) 或安慰剂,然后进行洗期.
- 使用CANTAB进行认知评估,测量动脉硬度,视网膜微血管和血清BDNF.
主要成果:
- 在五项选择反应时间测试中,AME补充剂显著减少了运动时间 (p < 0.05).
- 没有观察到记忆或执行功能的显著变化.
- 血清BDNF度显著增加 (p <0.05),而动脉硬度和视网膜微血管口径没有受到影响.
结论:
- 短期的AME补充剂对年轻成年人的注意力和精神运动速度产生了积极的影响.
- 血清BDNF水平的增加可能是这些认知改善的基础机制.
- 在本研究人群中,AME补充剂没有影响血管功能标志物.
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