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塑料伤口保护器与外科手术用手术用手术部位感染减少在开放的胃肠道手术:一个随机临床试验

Nina Yoo^1,2, Ji Yeon Mun², Bong-Hyeon Kye²

¹Department of Surgery, Seoul St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

|April 24, 2024

概括

与外科相比,塑料伤口保护剂在开放性胃肠道手术中显著减少了手术部位感染 (SSI). 这支持世卫组织在腹部手术中使用伤口保护剂的建议.

科学领域:

手术瘤学手术瘤学
预防传染病预防传染病
临床试验临床试验

背景情况:

手术部位感染 (SSI) 是常见的医院感染,给患者带来重大风险和医疗费用.
世界卫生组织 (WHO) 建议在腹部手术中使用伤口保护剂,以减轻SSI风险,尽管证据有限.

研究的目的:

评估双环塑料伤口保护剂在开放性胃肠道手术期间降低SSI率的有效性.
在开放的肠道外科手术中评估SSI减少,而不考虑腹腔内污染水平.

主要方法:

一个多中心,患者盲目的随机临床试验,涉及457名接受腹部开放肠道手术的患者.
患者被随机分配,接受双环塑料伤口保护剂或常规外科手术.
主要结局是手术后30天内SSI率.

主要成果:

伤口保护组的SSI率明显较低 (10.9%),相比手术软组 (20.5%),相对风险降低了46.81%.
该设备在减少清洁受污染的伤口中的SSI (RRR 43.75%) 和表面的SSI (RRR 42.50%) 中特别有效.
住院时间和整体术后并发症率在各组之间相似.

结论:

在开放式胃肠道手术中使用塑料伤口保护剂显著降低了手术部位感染的发生率.
这些发现支持世卫组织在腹部手术中使用伤口保护装置的建议,以提高患者的安全性.

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