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Updated: Jun 21, 2026

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在用[177Lu]Lu-PSMA-I&T治疗放射性干体后,使用人口药理动力学/药理动力学模型量化生物化学PSA动力学

Hinke Siebinga1,2, Berlinda J de Wit-van der Veen3, Daphne M V de Vries-Huizing3

  • 1Department of Pharmacy and Pharmacology, The Netherlands Cancer Institute: Antoni Van Leeuwenhoek, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands. h.siebinga@nki.nl.

EJNMMI physics
|April 24, 2024
PubMed
概括

这项研究开发了一种药理动力学/药理动力学 (PKPD) 模型,用于-177 PSMA (177Lu-PSMA) 治疗转移性割抵抗性前列腺癌. 该模型预测治疗反应,帮助患者选择和优化治疗结果.

关键词:
177Lu-PSMA-I&T的使用情况这不是nonmemem.这是PKPD的PKPD.在PSA响应过程中,PSA应答人口药理动力学模型前列腺癌是什么意思 前列腺癌是什么意思

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