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Updated: Jun 19, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
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富含白的α-2-甘氨蛋白1通过IL-6在小鼠牙周炎模型中影响骨破坏

Kazuhisa Ouhara1, Tasuku Takemura1, Yuri Taniguchi1

  • 1Department of Periodontal Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

Oral diseases
|April 24, 2024
PubMed
概括

富含白素的α-2-糖蛋白-1 (LRG1) 在牙周炎患者中升高,并通过INTERLEUKIN-6促进组织破坏. 这表明LRG1可能成为牙周炎的新型诊断标志物.

关键词:
葡萄牙牙牙病 Porphyromonas gingivalis 这种虫子是在IL-6中,IL-6是最常见的.骨质再吸收 骨质再吸收富含白的α-2-甘氨蛋白 1 1

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Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...