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Nkd1在Axin2的下游发挥作用,减弱Wnt信号传输

Ian Bell1, Haider Khan1, Nathan Stutt2

  • 1Department of Molecular and Cellular Biology, University of Guelph, Guelph, N1G 2W1 Ontario, Canada.

Molecular biology of the cell
|April 24, 2024
PubMed
概括

这项研究揭示了Axin2和Nkd1是如何调节Wnt信号的. 斑马鱼突变体显示Nkd1在Axin2的下游活动,Axin2单独影响Wnt活动,双重突变体拯救了一个没有眼睛的表型.

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