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Updated: Jun 28, 2025

Author Spotlight: Achieving High-Purity In Vitro Differentiation of Th17 Cells Using Cytokine Concentration Modulation
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Author Spotlight: Achieving High-Purity In Vitro Differentiation of Th17 Cells Using Cytokine Concentration Modulation

Published on: October 25, 2024

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类IIa HDAC4 和 HDAC7 在 Th17 细胞分化中协同调节基因转录

Ka Lung Cheung1, Li Zhao2, Rajal Sharma1

  • 1Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029.

Proceedings of the National Academy of Sciences of the United States of America
|April 24, 2024
PubMed
概括

类IIa组胺脱乙酶 (HDAC4/7) 对于T-辅助17细胞的分化和功能至关重要. 向HDAC4/7可能治疗性结肠炎等炎症性疾病.

关键词:
在HDAC4和HDAC7中.Th17细胞分化的过程发现药物的发现.基因转录 基因转录

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