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更高的产前焦虑预测了新生儿头发皮质醇的降低
LillyBelle K Deer1, Ella-Marie P Hennessey1, Jenalee R Doom1
1Department of Psychology, University of Denver, Denver, CO, USA.
Psychoneuroendocrinology
|April 24, 2024
概括
孕期孕妇怀孕相关的焦虑与较低的胎儿皮质醇水平有关,根据新生儿头发的测量. 这表明与怀孕相关的焦虑可能会影响胎儿发育,并可能是干预的目标.
科学领域:
- 神经内分泌学神经内分泌学
- 发展心理学 发展心理学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
背景情况:
- 产前葡萄皮质激素是胎儿编程的一个关键机制.
- 新生儿头发皮质醇反映了胎儿在第三季度暴露于皮质醇的情况.
- 通过新生儿头发测量胎儿皮质醇存在有限的研究.
研究的目的:
- 调查怀孕期间与新生儿头发皮质醇有关的怀孕相关焦虑和一般焦虑之间的联系.
- 为了确定焦虑水平是否预测胎儿在第三季度的皮质醇积累.
主要方法:
- 107名孕妇和他们的新生儿参与了这项研究.
- 与怀孕相关的焦虑和一般焦虑被评估使用验证的尺度 (PRAS,STAI) 在三个月.
- 层次线性建模分析了焦虑轨迹;新生儿头发皮质醇在出生后被测量.
主要成果:
- 较高的怀孕相关焦虑和怀孕早期的一般焦虑,以及较慢的怀孕相关焦虑下降,与较低的新生儿头发皮质醇有关.
- 在控制共变量后,与怀孕相关的焦虑仍然是显著的预测因素.
- 与怀孕相关的焦虑预测新生儿的皮质醇独立于一般焦虑.
结论:
- 较低的新生儿毛皮质醇,与较高的母亲怀孕相关的焦虑有关,可能对胎儿发育有影响.
- 与怀孕相关的焦虑,特别是在怀孕早期和更平坦的下降,是一个重要的因素.
- 孕妇怀孕相关的焦虑是未来干预策略的潜在目标,以支持胎儿编程.
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